Toxicological Assessment of ABATE (Tradename) (0,0,0',0'-Tetramethyl-0,0'-Thio-Di-P-Phenylene Phosphorothioate) Administered Orally and Dermally to Mated and Nonmated Female Rabbits, April 1983.

Abstract

This study was designed to assess the teratologic potential of ABATE following repeated oral or dermal administration of the compound to pregnant rabbits during the major period of organogenesis. There were no teratologic effects in New Zealand White rabbits associated with repeated oral or dermal administration of ABATE at levels which produced a toxic effect. Although these studies have shown that ABATE should not cause teratogenic effects in its intended use, chronic studies should be performed to further define any potential long term toxicity.

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Document Details

Document Type
Technical Report
Publication Date
Nov 02, 1983
Accession Number
ADA134545

Entities

People

  • Maurice H. Weeks
  • Richard A. Angerhofer

Organizations

  • United States Army Medical Command

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Body Weight
  • Chemical Synthesis
  • Chemistry
  • Experimental Design
  • Fertility
  • Health Services
  • Hygiene
  • Musculoskeletal Abnormalities
  • New Jersey
  • New York
  • New Zealand
  • Pest Control
  • Plant Exudates
  • Pregnancy
  • Skull
  • United States

Readers

  • Toxicology/Environmental Toxicology