The Chemical Characteristics of PGBx.
Abstract
It was first attempted to separate PGBx, a biologically active material obtained upon alkali treatment of 15-keto-prostaglandin-B1(1), into its components, determine their molecular weight and, finally, molecular structure. When it became clear that PGBx is too complex a mixture, model studies were begun. To investigate the mechanism by which the chemically active moiety in 15-keto-prostaglandin-B1 oligomerizes to PGBx under alkaline conditions, the condensation of 3-ethyl-4-(3'-ketopenten-1-yl) cyclopent-2-enone (2) was investigated.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 18, 1983
- Accession Number
- ADA135851
Entities
People
- K. Biemann
Organizations
- Massachusetts Institute of Technology