Correlation of Mutagenic, Carcinogenic and Co-Carcinogenic Effects of Chemical Substances. Granuloma Pouch Assay.

Abstract

The research project is concerned with the detection of premalignant and malignant cells induced in vivo in a novel assay system the granuloma pouch assay. Cells exposed to carcinogens in vivo can be studies for DNA damage, chromosomal aberrations, specific locus mutations and cell transformations. Various assays were developed to investigate the growth characteristics of normal, carcinogen-exposed and transformed granuloma pouch cells.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 1983
Accession Number
ADA137794

Entities

People

  • G. Zbinden

Tags

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Animals
  • Assays
  • Cancer
  • Carcinogens
  • Cell Line
  • Cells
  • Connective Tissue
  • Detection
  • Efficiency
  • Mutations
  • Neoplasms
  • Scientific Research
  • Switzerland
  • Tumor Cell Line
  • Universities

Readers

  • Molecular Genetics
  • Oncology and Biomarker-Based Cancer Detection.
  • Toxicology/Environmental Toxicology