Chemical Ionization Mass Spectrometry: New Methodology.
Abstract
The goal of this research program was to develop new methodology for the detection and characterization of organic molecules by mass spectrometry. Specific areas addressed included; gas phase ion molecule isotope exchange reactions for counting hydrogen atoms in specific organic structural environments, optimization of tandem mass spectrometry for the direct analysis of complex mixtures of organics, sequence analysis of peptides in mixtures by the combination of collision activated dissociation and tandem mass spectrometry, fragmentation mechanisms of negative ions, and construction of a tandem quadrupole mass spectrometer with improved sensitivity for operation in the FAB ionization mode in the mass range, 1,000 - 2,000 amu. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 08, 1984
- Accession Number
- ADA138037
Entities
People
- D. F. Hunt
Organizations
- University of Virginia