Fatty Acid Metabolism and Pulmonary Insufficiency Studies.

Abstract

A reproducible free fatty acid analysis was carried out with a total of 1407 studies being performed. The results of correlating this to respiratory distress in trauma patients revealed a trend correlating elevated free fatty acid levels with PO2-FiO2 ratios of 1.9, indicating respiratory distress. Patients with normal PO2-FiO2 ratios had relatively normal free fatty acid levels following injury. Animal studies were carried out during the first year showing a reduction of both cytochrome P-450 and mixed function amino oxidase (MFAO) activities following injury. Injury produces an elevation in free fatty acid levels in these animals.

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Document Details

Document Type
Technical Report
Publication Date
Oct 22, 1979
Accession Number
ADA138677

Entities

People

  • J. A. Moylan

Organizations

  • Duke University Hospital

Tags

DTIC Thesaurus Topics

  • Albumins
  • Arteries
  • Blood
  • Blood Proteins
  • Chemistry
  • Cytochromes
  • Diseases And Disorders
  • Elevation
  • Extraction
  • Fatty Acids
  • Measurement
  • Metabolism
  • Pharmacology
  • Proteins
  • Pulmonary Function
  • Pulmonary Insufficiency
  • Surgery

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