Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-38274, AI3-38276, and AI3-38279, US Department of Agriculture Proprietary Chemicals, February - November 1983.
Abstract
The technical grade chemicals produced no greater than mild primary irritation of the intact skin and of the skin surrounding an abrasion. The 24 percent (w/v) solutions of these chemicals in 95 percent ethanol which were applied during photoirritation studies produced mild to moderate primary irritation of the intact skin, without ultraviolet (UV) irradiation. Chemical AI3-38276 produced a photochemical irritant reaction upon irradiation with UV light which was significantly more severe than the primary irritation previously noted. Additionally, although these ethanol solutions were colorless, they produced a marked yellow discoloration of the skin upon application. All three chemicals produced moderate injury to the cornea and, in addition, produced some injury to the conjunctiva.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 03, 1984
- Accession Number
- ADA139966
Entities
People
- J. V. Wade
Organizations
- United States Army Medical Command