Blood Preservation Study.

Abstract

Although the 21 day shelf life of red cells stored in acid-citrate-dextrose or citrate-phosphate-dextrose solution represents a workable system for blood storage, it is unsatisfactory in three major respects: (1) A shelf life of only 21 days makes the stockpiling of blood impossible. (2) While blood is considered to be usable until the 21st day of storage, only about 70% of the red cells in 21 day-old units are useful to the patient. (3) The 2,3-diphosphoglycerate (2,3-DPG) content of blood stored in ACD declines rapidly after one or two days of storage, while in CPD the decline of 2,3-DPG levels is delayed for only one week. Work has been directed toward resolution of the three problems associated with liquid blood storage.

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Document Details

Document Type
Technical Report
Publication Date
Apr 30, 1979
Accession Number
ADA140159

Entities

People

  • E. Beutler

Organizations

  • City of Hope National Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Blood Preservation
  • Blood Storage
  • Calcium Hydroxide
  • Cells
  • Erythrocytes
  • Glucose
  • Glycolysis
  • Jet Propulsion
  • Measurement
  • Medical Personnel
  • Membrane Proteins
  • Metabolism
  • Military Operations
  • Shelf Life
  • Test And Evaluation

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