A Comparison of Methods Used for Determination of the 100% Survival of Preserved Red Blood Cells.
Abstract
Three methods were evaluated to determine which gave the most accurate 100% survival value from which to estimate the 24-hour posttransfusion survival of 51Cr-labeled preserved red blood cells: (1) indirect measurement of the recipient's red blood cell volume using 125I albumin and the total body area nomogram; and (3) extrapolation of the radioactivity associated with the red blood cells in the recipient's circulation after the transfusion. When less than 20% of the transfused survival values of between 80-100%, the three methods have comparable results. Data indicated that when nonviable red blood cells are rapidly removed from the circulation immediately after transfusion, the extrapolation method gives an underestimation of the 100% survival value, resulting in an overestimation of the 24-hour posttransfusion survival value.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 13, 1982
- Accession Number
- ADA140406
Entities
People
- A. X. Gray
- C. R. Valeri
- L. E. Pivacek
- R. Ouellet
Organizations
- Boston University