Therapeutic Effectiveness of Cryopreserved Autologous Platelets in the Treatment of Thrombocytopenic Dogs.

Abstract

Canine platelets were preserved in the frozen state with 6% DMSO in a -80 C mechanical freezer. The recovery of platelets after the freeze-thaw-wash procedure was about 70%, and posttransfusion recovery values were about 40% those of fresh platelets. The washed previously frozen platelets were hemostatically effective in supporting lethally irradiated dogs through prolonged periods of thrombocytopenia.

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Document Details

Document Type
Technical Report
Publication Date
Apr 08, 1982
Accession Number
ADA140419

Entities

People

  • A. J. Doty
  • A. J. Melaragno
  • C. R. Valeri
  • J. Dittmer
  • J. J. Vecchione

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Albumins
  • Blood
  • Blood Cells
  • Blood Transfusions
  • Blood Volume
  • Bone Marrow
  • Bones
  • Cells
  • Chlorides
  • Classification
  • Dilution
  • Freezing
  • Glucose
  • Sodium Compounds
  • Thrombocytopenia
  • Volume
  • Whole Body Irradiation

Fields of Study

  • Medicine

Readers

  • Immunology