Effects of Liquid Storage in a High pH Anticoagulant on the Circulation of Baboon Platelets.

Abstract

Baboon platelet-rich plasma (PRP) was stored in a 150 ml filter flask at 22 + or - 2 C for up to 15 days. The pH of the PRP was maintained at 7.4 by adding 6 + or N KOH or 6 N HCL during the storage period. Reduced 51 Chromium platelet survivals immediately after transfusion and reduced lifespan values were observed when the platelet-rich plasma was stored at 22 C at pH 7.4 for 3 days or longer. Significant contamination was seen in the platelet-rich plasma afer 7 days of storage.

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Document Details

Document Type
Technical Report
Publication Date
Apr 23, 1982
Accession Number
ADA140463

Entities

People

  • A. Doty
  • A. J. Melaragno
  • C. R. Valeri
  • J. G. White
  • Sarah B. Hall

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Albumins
  • Anticoagulants
  • Blood
  • Blood Transfusions
  • Blood Volume
  • Cells
  • Chemistry
  • Classification
  • Elements
  • Films
  • Liquids
  • Measurement
  • Radioactivity
  • Security
  • Survival
  • United States
  • Volume

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Immunology
  • Manufacturing Engineering.