Sutureless Vascular End-to-End Anastomosis.
Abstract
The objective of this project was to develop a means of rejoining severed vessels (end-to-end anastomosis) without using sutures. Two essential elements in the concept, an instrument to evert the vessel and a biocompatible, low-temperature (130 F/54 C), heat-shrinkage sleeve were developed. The sleeve, which contracts to accomplish the anastomosis, was developed by crosslinking (with ionizing gamma radiation) synthetic trans-1,4 polyisoprene. The crosslinked polymer was subjected to an acute toxicity screening program and proved to be highly biocompatible. The sutureless anastomosis technique was tested in-vitro on freshly excised pig carotid arteries however, there was insufficient funding available to provide for an evaluation of the technique in laboratory animals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 22, 1984
- Accession Number
- ADA140484
Entities
People
- J. J. Wozniak
Organizations
- Johns Hopkins University