Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Abstract

We have (1) characterized several of the major structural components of the Phlebotomus fever group viruses (Robeson, et al, 1979), and (2) isolated and begun to characterize several temperature sensitive (ts), conditional lethal, mutants of Punta Toro (PT) virus. In addition at the request of WRAIR, we have (3) demonstrated the feasibility of using oligonucleotide fingerprinting to distinguish Dengue (DEN) virus serotypes using cloned Aedes albopictus cells to produce labeled virus. These procedures have now been adopted by WRAIR personnel for their Dengue virus studies.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1979
Accession Number
ADA140720

Entities

People

  • D. H. L. Bishop

Organizations

  • University of Alabama

Tags

DTIC Thesaurus Topics

  • Acids
  • Amino Acids
  • Arbovirus Infections
  • Bunyaviridae
  • Bunyaviridae Infections
  • California
  • Electrophoresis
  • Gel Electrophoresis
  • Medical Personnel
  • Methionine
  • Nucleic Acids
  • Phlebotomus Fever
  • Rna Viruses
  • Structural Components
  • United States
  • Virion
  • Viruses

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology