Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Abstract

We have: (1) undertaken heterologous recombination analyses involving dualinfections with wild-type PT and SFS viruses, PT and CHG viruses, PT and ICO viruses, or PT and KAR viruses; (2) performed analyses of the homologous and heterorlogous virus interference capabilities of PT (or ICO) virus preparations that contain DI particles; (3) indicated that at the structural level the tick-borne uukuviruses (Uukuvirus genus, Bunyaviridae family) closely resemble phleboviruses; characterized the unassigned tick-borne Dhori (DHO) virus, a virus that heretofore has been considered as a possible member of the family, has been undertaken in order to determine if this virus has the structural attributes of phleboviruses (or members of other defined genera of the family); and (5) cloned and sequenced complete copies of influenza A/RR/8/34 RNA segments 2 and 3, as well as bunyavirus SSH S RNA species.

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Document Details

Document Type
Technical Report
Publication Date
Aug 28, 1982
Accession Number
ADA140721

Entities

People

  • D. H. L. Bishop

Organizations

  • University of Alabama

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Animal Diseases
  • Antigens
  • Bunyaviridae
  • Cells
  • Gel Electrophoresis
  • Genetic Code
  • Immune Serums
  • Medical Personnel
  • Phlebotomus Fever
  • Ribonucleic Acids
  • Rna Viruses
  • Structural Components
  • Viral Structures
  • Virion
  • Virology
  • Viruses

Fields of Study

  • Biology

Readers

  • Computational Modeling and Simulation
  • Molecular Genetics
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology