The Acute Effects of Thyrotropin Releasing Hormone on Reaction Times.
Abstract
The acute effects of thyrotropin releasing hormone (TRH) on human simple reaction time (SRT), choice reaction time (CRT), and information processing time (PT) were investigated using an electronic reaction time tester. The tester presented visual stimuli, and, to determine its statistically significant (p < or = .05) modes of operation, a pilot study was conducted with sixteen subjects (Ss). Left and right-handed performance of SRT and CRT tasks were determined to be beneficial for the primary study. Ten, right-handed male Ss participated in the double-blind TRH study. Ss acted as their own controls, so two sessions were required for each S, one involving an injection (I) of TRH (500 micrograms) and another a saline injection (1 normal). For acute time frame analysis, seven test periods, from I-20 minutes to I+120 minutes, were included in each session. With TRH, SRT increased significantly (p < or = .05) at I+5 minutes, probably due to the neurological effects of TRH. CRT decreased significantly in TRH and saline sessions at I+90 and +120 minutes, and PT decreased significantly at I+60, +90, and +120 minutes in TRH sessions. However, analysis revealed that no TRH-session times were significantly better than saline-session times. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1982
- Accession Number
- ADA141039
Entities
People
- N. E. Michel
Organizations
- Air Force Institute of Technology