Motor Performance in Irradiated Rats as a Function of Radiation Source, Dose, and Time Since Exposure.
Abstract
The study reported here has employed a single species (rats) and a single motor task (rotarod), and has evaluated performance as a function of time after irradiation exposure across a fixed dose range (0-1200 rads) using four radiation sources (electrons, neutrons, protons, and X-rays). Only minor differences in performance were noted as a function of radiation source, with neutrons producing the largest deficits. All sources produced a clear dose-response curve for each of the four times (1, 8, 15, and 22 days after irraditaion). The LD50/15 for the various exposures were found to be: X-rays, 1125 rads; electrons, 810 rads; protons, 675 rads; and neutrons, 265 rads.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1984
- Accession Number
- ADA141209
Entities
People
- K. A. Hardy
- L. B. Anderson
- S. Richards
- T. G. Wheeler
Organizations
- United States Air Force School of Aerospace Medicine