Dermal Sensitization Potential of the Holston Compounds: Virgin DMSO (Dimethyl Sulfoxide), DMSO Recycle Solvent, and DMSO Evaporator Sludge.

Abstract

The Holston Compounds designated Virgin DMSO (TP014), DMSO Recycle Solvent (TP013) and DMSO Evaporator Sludge (TP015) were tested for dermal sensitization potential on guinea pigs. The study was conducted in compliance with the Good Laboratory Practice Regulations. The results from this study were not conclusive, but there was some evidence which suggests that the test compounds might be weak sensitizers. The test compounds caused mild irritation responses which were difficult to distinguish from weak sensitizing responses.

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Document Details

Document Type
Technical Report
Publication Date
May 20, 1984
Accession Number
ADA142926

Entities

People

  • C. M. Lewis
  • D. W. Korte Jr.
  • Y. C. Johnson

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Animals
  • Biological Sciences
  • Biomedical Research
  • Detectors
  • Flow Rate
  • Health
  • Laboratory Animals
  • Liquid Chromatography
  • Melting Point
  • Military Research
  • Molecular Weight
  • Rdx
  • Rodents
  • Toxicity
  • Toxicology
  • United States Government

Readers

  • Atmospheric Science/Meteorology
  • Environmental Engineering.
  • Toxicology/Environmental Toxicology