The Effect of WR 149024 on Survival Following Hemorrhage in Conscious Rats.

Abstract

The effect of WR 149024, an alpha receptor antagonist, on survival following hemorrhage with no volume replacement therapy was investigated. WR 14902 (either 5.0 or 50.0 mg/kg) was administered intraperitoneally to conscious rats during exsanguination. Both WR 149024 treatments caused a significant decrease in survival (p<0.021), compared with water-injected controls.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1983
Accession Number
ADA142952

Entities

People

  • David F. Brown
  • R. F. Bellamy

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Arteries
  • Blood
  • Blood Transfusions
  • Blood Volume
  • Body Weight
  • Casualties
  • Combat Casualty Care
  • Department Of Defense
  • Hemorrhage
  • Hemorrhagic Shock
  • Laboratory Animals
  • Military Medicine
  • Resistance
  • Survival
  • United States Government
  • Volume

Readers

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