Toxicokinetics of Hydrazine Administered Percutaneously to the Rabbit
Abstract
The percutaneous absorption of various aqueous concentrations of hydrazine over selected time periods has been studied. Duration of hydrazine exposure and hydrazine concentration correlated closely with the percent dose absorbed and peak serum hydrazine concentration. The data suggested that about 70% of the available hydrazine in H70 is still unabsorbed two minutes following hydrazine application. There was an increase in serum hydrazine concentration following removal of hydrazine from the skin surface suggesting the existence of an epidermal compartment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 13, 1984
- Accession Number
- ADA143122
Entities
People
- C. T. Olson
- John P. Murphy
- M. E. Andersen
- R. H. Bruner
- W. C. Keller
Organizations
- Air Force Research Laboratory