Suppression of the Immune Response by Synthetic Adjuvants.

Abstract

Two classes of synthetic immunoadjuvants, the muramyl di-peptides, and the polyribonucleotide complexes, have the capacity to either elevate or suppress the immune response depending on the time of their administration relative to antigen. The long term objectives of this contract are to define the cell and molecular signals associated with the in vivo suppression of the immune response of Balb mice by each of these classes of non-toxic adjuvants.

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Document Details

Document Type
Technical Report
Publication Date
Aug 24, 1984
Accession Number
ADA145073

Entities

People

  • A. G. Johnson

Organizations

  • University of Minnesota Duluth

Tags

DTIC Thesaurus Topics

  • Antigens
  • Biological Factors
  • Biological Sciences
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cells
  • Chemistry
  • Infectious Diseases
  • Lymphatic System
  • Lymphocytes
  • Macrophages
  • Microbiology
  • Military Research
  • Peptides
  • Proteins
  • Tissues

Fields of Study

  • Biology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Immunology