Experimental Measurements of the Kinetic Evolution of Cluster Size Distributions with Applications to the Fractal Structure of Antigen-Antibody Clusters,
Abstract
In previous work, we have used a Nanopar resistive pulse analyzer to determine the temporal evolution of the distribution of clusters formed by antigen coated latex microspheres cross linked by the complementary antibody. This antigen-antibody system is conceptually isomorphic to an organic polymer reaction involving RAf units (latex microspheres with f active antigens) cross linked by B2 units (complementary antibody) with only A-B bonding allowed. The form of the cluster size distribution was studied as a function of the time, concentration of RAf units, and concentration of B2 units. The experimental results were interpreted theoretically in terms of solutions of the unidirectional Smoluchowski equations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1984
- Accession Number
- ADA145791
Entities
People
- D. Johnston
- G. Benedek
Organizations
- Massachusetts Institute of Technology