Dermal Sensitization of 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazocine.

Abstract

The explosive by-product, 1-acetyloctahydro-3,5,7-trinitro-1,3,5,7-tetrazocine (SEX), was tested for dermal sensitization potential on guinea pigs. The study was conducted in compliance with the Good Laboratory Practice Regulations. The absence of erythema in the test animals during the study indicated SEX is a non-sensitizer when applied topically in saline according to the closed patch dermal sensitization technique of Buehler. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Aug 08, 1984
Accession Number
ADA146826

Entities

People

  • C. M. Lewis
  • D. W. Korte Jr.
  • Y. C. Johnson

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Anhydrides
  • Animals
  • Bioengineering
  • Biological Sciences
  • Biomedical Research
  • Chemical Analysis
  • Chemical Synthesis
  • Chemistry
  • Materials
  • Military Research
  • Organic Chemistry
  • Quality Control
  • Sodium
  • Sodium Compounds
  • Toxicology
  • United States

Fields of Study

  • Chemistry

Readers

  • Environmental Engineering.
  • Toxicology/Environmental Toxicology