Mutagenic Potential of: 4-Nitrophenyl Dimethyl Phosphinate (TA007) using the Sex-Linked Recessive Lethal Test in Drosophila melanogaster.

Abstract

4-Nitrophenyl dimethyl phosphinate (TA007) has a potential as a prophylactic agent in nerve agent poisoning. Mutagenic activity of this compound was assayed using the Sex-Linked Recessive Lethal test in Drosophila melanogaster. TA007 was determined to be non-mutagenic following 72-hour feeding exposures to 0.01 and 0.005 mM concentrations.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1984
Accession Number
ADA148331

Entities

People

  • N. R. Powers
  • P. D. Mauk
  • Z. A. Mehr

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Biological Sciences
  • Biomedical Research
  • California
  • Chromosomes
  • Diptera
  • Drosophila
  • Genetics
  • Identification Systems
  • Laboratory Animals
  • Military Research
  • Nerve Agents
  • Poisoning
  • Scientific Research
  • Toxicology
  • United States

Readers

  • Molecular and genetic basis of cancer.
  • Toxicology/Environmental Toxicology