Acute Oral Toxicity (LD50) of 4-Nitrophenyl Monochloromethyl (Phenyl) Phosphinate (TA009) in Male Rats

Abstract

The acute oral toxicity of 4-nitrophenyl monochloromethyl (phenyl) phosphinate was determined in male, albino, Sprague-Dawley rats by using the oral gavage dose method. LD1, LD50, and LD95 with the 95% confidence limit were calculated by probit analysis. The LD50 was 203 mg/kg with the 95% confidence limit (142 mg/kg, 292 mg/kg). The formulation falls in the very toxic range.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1984
Accession Number
ADA148337

Entities

People

  • C. W. White
  • Janna Rodriguez
  • T. P. Kellner

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Biomedical Research
  • Body Weight
  • Chemical Warfare Agents
  • Computers
  • Confidence Limits
  • Data Science
  • Factor Analysis
  • Hydrolysis
  • Information Science
  • Lethal Dosage
  • Medical Personnel
  • Military Research
  • Physicians
  • Statistical Analysis
  • Toxicology
  • United States

Fields of Study

  • Chemistry

Readers

  • Toxicology/Environmental Toxicology