Neurophysiological Bases of Event-Related Potentials.
Abstract
In order to more fully understand the physiological and psychological significance of event-related potentials, cortical and subcortical recordings are being obtained from monkeys performing in operant-conditioning tasks. Six animals were trained on the cued reaction-time task at SRI International and were subsequently implanted with electrodes capable of recording transient and sustained evoked potentials and massed--unit activity. Two monkeys were trained on an odd-ball task at Stanford University, and electrodes were implanted so that the subcortical generators of the P300 wave could be assessed. At SRI slow potential changes were observed in a variety of cortical and subcortical regions and were observed to change as a function of discrimination, proportionality of stimuli, the interstimulus interval, and dose of an anticholinergic drug.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1984
- Accession Number
- ADA148482
Entities
People
- C. S. Rebert
- K. H. Pribram
- M. B. Hennessy
- M. M. Prim
Organizations
- SRI International