Genetic Characterization of Insect Vectors of Disease.

Abstract

The proposed projects involved population genetic analysis of Aedes aegypti. The main technique employed is gel electrophoresis of soluble proteins followed by staining for specific enzyme activity. Using this method we have identified 22 enzyme loci in this mosquito, of which 11 are particularly variable (polymorphic) and useful for our studies. The objectives of the research are to study allelic variation at these loci in order to answer the following questions about A. aegypti: (1) How genetically variable are populations? (2) How much genetic differentiation exists between populations? (3) Can we define areas within the distribution of A. aegypti which have populations genetically similar and differentiated from other areas? (4) Do the world-wide patterns of genetic variation in this vector correspond in any way to patterns of diseases transmitted by A. aegypti?

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1982
Accession Number
ADA148604

Entities

People

  • J. R. Powell

Organizations

  • Yale University

Tags

DTIC Thesaurus Topics

  • Africa
  • Central America
  • Computer Programs
  • Dengue
  • Disease Vectors
  • East Africa
  • Frequency
  • Genetic Structures
  • Genetic Variation
  • Genetics
  • Geographic Regions
  • Islands
  • Materials
  • Population Genetics
  • South America
  • United States
  • Yellow Fever

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.
  • Regression Analysis.
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology