A Spectroelectrochemical Investigation Oxidation of the Bilirubin IX-Alpa in Dimethylformamide.

Abstract

This electrochemistry of bilirubin IX-alpha in N,N-dimethylformamide has been investigated by cyclic voltammetry, ac voltammetry, modulated specular reflectance spectroscopy, small amplitude ac reflectance spectroscopy, OTTLE cell spectroelectrochemistry, and conventional spectroscopy. The data suggest a CECEC mechanism for oxidation of bilirubin to biliverdin. The oxidation potential for the mono-deprotonated bilirubin to its cation radical is +0.10 V, and for the carbonium ion/free radical couple, -0.86 V vs Ag/Ag+ (0.10 M).

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Document Details

Document Type
Technical Report
Publication Date
Nov 28, 1984
Accession Number
ADA148662

Entities

People

  • A. S. Hinman
  • J. F. Mcaleer
  • J. R. Pradko
  • Stanley Pons

Organizations

  • University of Utah

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Carboxylic Acids
  • Chemical Reaction Properties
  • Chemical Reactions
  • Chemical Synthesis
  • Chemistry
  • Chromophores
  • Electrochemical Reactions
  • Electrochemistry
  • Electrodes
  • Electron Transfer
  • Frequency
  • Intensity
  • Materials
  • Military Research
  • Modulation
  • Oxidation

Fields of Study

  • Chemistry

Readers

  • Electrochemical Surface Science
  • Organic Chemistry