Acute Toxicity of Thionyl Chloride Vapor for Rats

Abstract

Rats were exposed to thionyl chloride vapor for one hour to determine the acute inhalation toxicity of this compound. The thionyl chloride was completely hydrolyzed to sulfur dioxide and hydrogen chloride gases when evaporated in air. The calculated LD50 expressed as thionyl chloride was 500 ppm for a one hour single exposure and the acute toxicity of the hydrolyzed mixture was comparable to a theoretical calculation for additive effects of the mixture. The acute toxicity of thionyl chloride appears to be much lower than previously reported.

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Document Details

Document Type
Technical Report
Publication Date
Nov 19, 1984
Accession Number
ADA148952

Entities

People

  • E. R. Kinkead
  • R. L. Einhaus

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  • University of California, Irvine

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  • Biomedical

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