Development of Special Biological Products.

Abstract

Tissue culture: Three production lots of FRhL-2, one each of MRC-5 and primary Duck and two lots of A. albopictus (C6-36) were stabilized and frozen. Eight lots of cells for use in testing were processed. Vee (C-84) Vaccine Development: Potency testing on Lots C-84-6 and C-84-7 was completed. A second addendum covering VEE, inactivated, dried (TSI-GSD 205) vaccine lots C-84-2 through C-84-7 was prepared and transmitted to USAMRIID. WEE Vaccine Development: Testing of WEE vaccine seed virus, strain CM4884 was completed. A test for adventitous agents in the seed was negative. Rift Valley Fever Vaccine Development: The tests to certify the RVF virus, strain ZZ501, for vaccine production were completed. Junin Virus Vaccine Development: Safety tests on four fluids prepared at USAMRIID were conducted. Two freeze-drying runs using various suspending diluents were done. Korean Hemorrhagic Fever: A total of 20 lots of 10 spot FA slides were produced and shipped. Tularemia Vaccine Development: Three batches of tularemia vaccine bacteria, strain LVS, were produced in a fermentor.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1983
Accession Number
ADA150862

Entities

People

  • A. Shelokov
  • C. K. Lee
  • D. E. Craig
  • G. R. French
  • J. L. Demeio

Tags

DTIC Thesaurus Topics

  • Animals
  • Anti-Bacterial Agents
  • Bacteria
  • Biological Products
  • Body Fluids
  • Cells
  • Freeze Drying
  • Health Services
  • Immune Serums
  • Infectious Diseases
  • Medical Personnel
  • Rift Valley Fever
  • Rift Valleys
  • Rodents
  • Tissue Culture
  • Vaccines
  • Viruses

Fields of Study

  • Biology

Readers

  • Microbial Pathology
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology