Studies to Control Endemic Typhoid Fever in Chile

Abstract

A multi-faceted program of applied research was undertaken to control endemic typhoid fever in Santiago, Chile. These studies included: (1) A Case/Control study to identify risk factors and incriminate specific vehicles involved in transmission of S. typhi. (2) Prevalence of chronic S. typhi carriers in persons with cholecystitis. (3) Simple serologic and other screening tests to identify chronic S. typhi carriers. (4) A simple, practical, non- surgical treatment for chronic S. typhi carriers. (5) An evaluation of the sensitivity and specificity of diagnosing acute typhoid fever by identifying Vi antigen in urine. (6) A field-trial of Ty21a attenuated S. typhi vaccine. Keywords: Salmonellosis; Immunization; and Epidemiology, and Vi antigen.

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Document Details

Document Type
Technical Report
Publication Date
Jan 30, 1983
Accession Number
ADA153979

Entities

People

  • Claudio Lanata
  • Mary L. Clements
  • Myron M. Levine
  • Robert E. Black
  • Stephen Sears

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Anti-Infective Agents
  • Biliary Tract Diseases
  • Bone Marrow
  • Gram-Negative Bacterial Infections
  • Health
  • Health Care
  • Health Services
  • Immune Serums
  • Infection
  • Infectious Diseases
  • Medical Personnel
  • Public Health
  • Regression Analysis
  • Standards
  • Surgery
  • Therapy

Fields of Study

  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Immunology
  • Microbial Pathology

Technology Areas

  • Biotechnology