Effects of Long-Term Low-Level Radiofrequency Radiation Exposure on Rats. Volume 8. Evaluation of Longevity, Cause of Death, and Histopathological Findings.
Abstract
For 25 months 100 male SPF (Specific-Pathogen-Free) rats were exposed to pulsed 2450-MHz circularly polarized microwaves, at an average power density of 0.48 mW/sq. cm; another 100 rats served as sham-exposed controls. Evaluation of survival time showed no statistically significant difference during any phase of the life span. There was no association between a specific cause of death and the treatment condition. Except for rats that died of urinary tract blockage, there is some indication that the survival times were longer in the exposed animals. Of 1992 nonneoplastic lesions, only glomerulonephropathy was less frequently observed in the exposed animals; no other lesions differed statistically. Of 192 neoplastic lesions observed, no specific increase was seen in any specific organ or tissue. Collapsing of the data and an analysis with respect to the occurrence of all neoplasms showed no difference for benign lesions, but a statistically higher incidence of primary malignancies in the exposed animals than in the sham exposed. The biological significance of this finding is questionable at this time.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1985
- Accession Number
- ADA154283
Entities
People
- C. K. Chou
- David Thompson
- J. Crowley
- L. L. Kunz
- R. B. Johnson