The Effect of +Gx Acceleration on Platelet Activation as Determined by Plasma Platelet Factor 4 Levels.
Abstract
Six healthy men were exposed to a +Gx acceleration (chest to back) profile with peak +Gx levels of 5, 8, and 9 G. Platelet factor 4 levels and platelet counts were measured prior to and immediately following the acceleration exposure. The +Gx acceleration exposure did not affect either parameter, however elevated pre-acceleration platelet factor 4 levels were found in five of six subjects. The possible significance of this is discussed. Future space missions will expose man to unique combinations of environmental stresses. Decompression and +Gx acceleration exposure is one such combination. It is important to determine if there are some features of these stresses which by themselves are benign, but in combination can result in problems for the astronaut. At acceleration levels greater +4 Gx, the subject experiences chest pain. Breathing becomes difficult, causing the subject to become dyspneic and to breathe using his abdominal muscles. Above +6Gx, pulmonary volumes are reduced, and the subject is unable to move his arms and legs.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1985
- Accession Number
- ADA155881
Entities
People
- C. T. Olson
- F. S. Cramer
- G. A. Mcdonald
- L. L. Howell
- T. J. Jennings
Organizations
- Air Force Research Laboratory