Effect of Dermal Applications of Paranitrophenol on the Reproductive Functions of Rats.

Abstract

The reproductive hazards of paranitrophenol, a leather fungicide, was assessed in rats. Compound, at various dosage levels, was administered dermally to parental and subsequent two generations. No significant differences in mating, pregnancy, behavior or growth were found when PNP-treated groups were compared with control groups. All rats receiving PNP, dermally, experienced a dose-related pattern of skin irritation. Paranitrophenol was found not be a reproductive hazard in rats.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1985
Accession Number
ADA157120

Entities

People

  • R. A. Angerhofer

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Animals
  • Body Weight
  • Breeding
  • Demographic Cohorts
  • Environmental Protection
  • Fertility
  • Fungi
  • Fungicides
  • Health
  • Health Services
  • Materials
  • Plastic Explosives
  • Pregnancy
  • Test Methods
  • Tissues
  • United States
  • Urogenital System

Readers

  • Toxicology/Environmental Toxicology