Ipso Nitration. Regiospecific Nitration via Ipso Nitration Products.
Abstract
Work has been focused on developing efficient methods of preparing 4-alkyl-nitrocyclohexadienones and 4-alkyl-4-nitrocyclohexadienols by batch and flow processes. Detailed studies of the thermal and acid-catalyzed rearrangements of 4-alkyl-4-nitrocyclohexadienones have been made, leading to mechanistic assignments that may have broader implications to the mechanism of direct nitration of reactive aromatics with nitronium ion. Similarly, the hydrolysis reactions of nitrodienols in both acidic and neutral aqueous media have been explored in detail. Studies of the reaction chemistry of nitrodienyl halides and nitrodienyl sulfonate esters have continued.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 20, 1985
- Accession Number
- ADA157688
Entities
People
- P. C. Myhre
Organizations
- Harvey Mudd College