Health Hazard Evaluation of Liquid Monopropellants. Phase 5. Comparative Inhalation Toxicities of LGP 1776, LGP 1845, and HAN (Hydroxylammonium Nitrate)
Abstract
A comparison of the inhalation toxicities of two liquid gun propellant (LGP) formulations, LGPs 1776 and 1845, was made using rats. Also assessed was the major chemical component of each, hydroxylammonium nitrate (HAN). Rats exposed to saturated vapors of the two LGPs for 8 hours were unaffected. Following single acute aerosol exposures, LGP 1845 was more toxic, with deaths occurring at concentrations of 1350 to 1603 mg/cu m. After 5 or 10 daily aerosol exposures to the three formulations, comparable dose-dependent effects were noted. These included hematological, organ-to-body weight ratio, and pathological changes, generally at the highest exposure level of 600 mg/cu m. It is concluded that acute exposures to LGP vapors should not be hazardous to man. Also inferred is that the effects of repeated, sublethal exposures to LGPs 1776 and 1845 are quantitatively similar to those observed with HAN, the major chemical component.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1985
- Accession Number
- ADA159090
Entities
People
- H. L. Snodgrass Jr.
Organizations
- United States Army Medical Command