Chemical Characterization and Toxicologic Evaluation of Airborne Mixtures. Tumorigenicity Studies of Diesel Fuel-2, Red Smoke Dye and Violet Smoke Dyes in the SENCAR Mouse Skin Tumorigenesis Bioassay System

Abstract

The tumorigencities of Diesel Fuel-2, Red Smoke Dye and Violet Smoke Dye were tested in the SENCAR Mouse Skin Bioassay System. The Diesel Fuel-2 gave a significant tumor response when tested as a tumor promoter but negative results when tested as a complete carcinogen. There were no tumor responses to either the Red or Violet Smoke Dyes when tested as complete carcinogens. Although a few tumors occurred in the Red and Violet Smoke Dye tumor initiation studies, the response was not significantly different from that of the controls.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1985
Accession Number
ADA159728

Entities

People

  • L. L. Triplett
  • R. J. M. Fry
  • T. J. Slaga

Organizations

  • Oak Ridge National Laboratory

Tags

DTIC Thesaurus Topics

  • Airborne
  • Aromatic Hydrocarbons
  • Assays
  • Biomedical Research
  • Cancer
  • Carcinogens
  • Chemical Synthesis
  • Chemistry
  • Colored Smokes
  • Diesel Fuels
  • Fuels
  • Lactones
  • Organic Chemistry
  • Plastic Explosives
  • Test And Evaluation
  • United States
  • United States Government

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Molecular Biology and Genetics
  • Toxicology/Environmental Toxicology