The Production of RhO(D) Negative Erythrocytes.

Abstract

Attempts are being made to modify or destroy the Rh (D) antigen under conditions which will produce Rh negative erythrocytes of transfusable quality. To this end the effects of various lipase and membrane perturbants are being examined. Isolation and biochemical characterization of the D antigen is also being undertaken in order to gather information which will help formulate ways of modifying its expression. Originator-supplied keywords include: Phospholipases and the modification of D antigenicity.

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Document Details

Document Type
Technical Report
Publication Date
Jun 24, 1985
Accession Number
ADA160775

Entities

People

  • Joel Goldstein

Organizations

  • New York Blood Center

Tags

DTIC Thesaurus Topics

  • Agglutination
  • Amino Acids
  • Antibodies
  • Cell Membrane
  • Cells
  • Erythrocytes
  • Fatty Acids
  • Immune Serums
  • Incubation
  • Membrane Lipids
  • Membrane Proteins
  • Membranes
  • Military Research
  • Molecular Weight
  • New York
  • Production
  • Proteins

Readers

  • Database Systems and Applications
  • Immunology
  • Molecular and Cellular Biochemistry