An Experimental Trial to Test the Efficacy of Temazepam to Induce Sleep and Improve Subsequent Performance during Partial Sleep Deprivation and Circadian Rhythm Desynchronosis.

Abstract

This thesis presents a strategy for reducing jet lag induced performance degradations by resetting rhythms during prolonged rapid transmeridian flight is studied. Thirty-four aircrew member passengers on a C-141 flight were given temazepam or placebo during the flight from Oklahoma to Saudi Arabia for induction of sleep in a period compatible with sleep cycle at the destination, but 'out-of-sync' with previous patterns set at home station, Mental performance and circadian rhythm patterns were tested per-flight, inflight and post-flight by several measurements including a computerized performance battery. The results indicated that in the temazepam group performance was improved to near baseline levels. The restorative power of temazepam induced sleep during a period of partial sleep deprivation and temazepam's ability to reset circadian rhythms prior to arrival in the new time zone were demonstrated. Index words: Restoril, Jet Lag, Transmeridian Flight.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1985
Accession Number
ADA160795

Entities

People

  • J. E. Mcghee

Organizations

  • Air Force Institute of Technology

Tags

Communities of Interest

  • Biomedical
  • Human Systems

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Analysis Of Variance
  • Circadian Rhythms
  • Data Analysis
  • Flight Crews
  • Health Services
  • Human Behavior
  • Human Factors Engineering
  • Jet Lag
  • Medical Personnel
  • Pattern Recognition
  • Performance Tests
  • Physicians
  • Side Effects
  • Surveys
  • United States

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology