Acute Toxicity Studies on Two Air Force Hydraulic Fluids (MLO 82-233 and MLO 82-585)

Abstract

This report describes results of investigations into the acute toxic properties of two operational Air Force hydraulic fluids, MLO 82-233 and MLO 82- 585. Various routes of administration were investigated including inhalation, dermal, and oral to rats, guinea pigs, rabbits, and chickens. No acute toxicity occurred in rats with either hydraulic fluid as a results of oral or inhalation exposure at the maximum concentration tested. Dermal exposure of rabbits resulted in no mortalities with either hydraulic fluid. One hydraulic fluid, MLO 82-585, was found to be a moderate skin irritant but neither fluid caused ocular irritation nor did they produce a sensitization response in guinea pigs. Neither fluid would be considered to be a delayed neurotoxin. Keywords: Lesions; Organophosphorous compounds.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1985
Accession Number
ADA163174

Entities

People

  • C. L. Gaworski
  • E. R. Kinkead
  • J. R. Hotron
  • R. A. Salomon

Organizations

  • University of California

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Animals
  • Biodiesels
  • Biomedical Research
  • Body Weight
  • Fluids
  • Hydraulic Fluids
  • Hydrocarbons
  • Materials
  • Medical Personnel
  • Nerve Tissue
  • Peripheral Nervous System
  • Plant Oils
  • Rodents
  • Test Methods
  • Toxic Hazards
  • Toxicity

Readers

  • Combustion and Flow Dynamics.
  • Rocket Propulsion.
  • Toxicology/Environmental Toxicology