The Experimental Determination of Safe Atmospheric Exposure Concentrations of JP-10 Jet Fuel

Abstract

Four animal species were exposed for 1 year to 100 ppm (556 cu mg/m) JP-10 to determine its long-term toxic and oncogenic effects. Rats, mice, and hamsters were maintained for 1 year postexposure, while dogs were held for 5 years postexposure. Mean body weights of exposed hamsters and make rats were lower than controls during exposure. Weight recovery occurred in hamsters, but not in male rats during postexposure phase of the study. Significant JP-10 exposure related effects were renal tubular nephrosis together with an increase in benign and malignant renal cell tumors in male rats.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1985
Accession Number
ADA163179

Entities

People

  • C. C. Haun
  • E. R. Kinkead
  • Edmond H. Vernot
  • James Douglas MacEwen
  • R. A. Salomon
  • R. H. Bruner

Organizations

  • University of California

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Biliary Tract
  • Biomedical Research
  • Blood
  • Body Weight
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Ecotoxicology
  • Endocrine Glands
  • Jet Engine Fuels
  • Kidney Diseases
  • Neoplasms
  • Rodents
  • Tissues
  • Toxic Hazards

Readers

  • Toxicology/Environmental Toxicology