Dermal Sensitization Potential of Guanidine Hydrochloride in Guinea Pigs

Abstract

Nitroguanidine is being evaluated by the US Army as a replacement for the nitrocellulose component of certain propellants/munitions. Guanidine hydrochloride was tested for its potential to produce sensitization via contact with the skin. Testing was performed on male guinea pigs by using the Buehler Dermal Sensitization method. No evidence of dermal sensitization to guanidine hydrochloride was obtained in this study.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 09, 1986
Accession Number
ADA164655

Entities

People

  • Don W. Korte Jr.
  • Earl W. Morgan
  • Gerald F. Hiatt

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Biological Sciences
  • Biomedical Research
  • California
  • Environmental Protection
  • Guanidines
  • Immune System
  • Laboratory Animals
  • Materials
  • Military Research
  • Nitroguanidine
  • Rodents
  • Toxicology
  • Triple Base Propellants
  • United States
  • United States Government

Fields of Study

  • Biology

Readers

  • Agricultural Chemistry/Soil Science
  • Materials Science and Engineering.
  • Molecular and Cellular Biochemistry