Primary Eye Irritation Potential of Nitroguanidine in Rabbits.

Abstract

The potential of nitroguanidine to produce primary eye irritation was evaluated in male New Zealand rabbits by using a modified Draize method. Nitroguanidine produced no response indicative of a potential to cause irritation upon direct contact with the eye. Slight conjunctival vasodilation was the most serious response observed. Keywords: Mammalian toxicology, Ocular toxicity.

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Document Details

Document Type
Technical Report
Publication Date
Jan 09, 1986
Accession Number
ADA164675

Entities

People

  • Don W. Korte Jr.
  • Gerald F. S. Hiatt
  • Steven K. Sano

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Bioengineering
  • Biological Sciences
  • Biomedical Research
  • Blood Vessels
  • Cornea
  • Eye
  • Materials
  • Medical Personnel
  • Military Research
  • New Zealand
  • Nitroguanidine
  • Toxicity
  • Toxicology
  • Triple Base Propellants
  • United States
  • United States Government

Readers

  • Toxicology/Environmental Toxicology