Investigations Regarding Anesthesia during Hypovolemic Conditions.
Abstract
The physiological management of moderately and severely wounded soldiers was studied with the objectives of (a) improving the return-to-duty rate of the combat-injured, (b) reducing morbidity and mortality of the combat-injured, and (c) reducing resource (primarily material and logistical support) utilization by Army medical field facilities. The research examines the interactions of anesthetic agents appropriate for use in a combat environment with hemorrhage. Swine are used as the experimental model, examining the rationale and physiology of use of nitrous oxide, enflurane, isoflurane, halothane, thiopental and ketamine for induction of anesthesia during the hypovolemic condition. We have found swine to be an excellent laboratory model for the study of hemorrhage, and the interaction of anesthetic agents with hemorrhage. Keywords: Combat casualty management; Hemorrhage; Anesthesia; Physiology cardiovasculat system; and Renin-angiotensin.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 25, 1983
- Accession Number
- ADA168110
Entities
People
- Richard B. Weiskopf
Organizations
- University of California, San Francisco