Endocrine and Pulmonary Response to Hemorrhagic Shock.
Abstract
Control and pancreatectomized-adrenalectomized rhesus monkeys were shown to exhibit comparable urinary nitrogen excretion rates and to have similar levels of metabolic dysfunction in isolated skeletal samples. Nutritional support with 50 percent dextrose with sufficient insulin to prevent hyperglycemia profoundly altered the metabolism of subsequently isolated skeletal muscle and prevented the induction of a nitrogen catabolic state by hemorrhagic shock. Subclassifications of acute respiratory failure based on pathophysiologic alterations are described. In animal work, changes following the infusion of oleic acid may be distinguished from E. coli. In humans, the lung changes following aneurysm surgery are different from those seen with sepsis. The metabolic functions of the lungs have been examined and found to be causative in inducing cardiac depression with high levels of PEEP.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 1976
- Accession Number
- ADA170129
Entities
People
- Herbert B. Hechtman
- Richard H. Egdahl
Organizations
- Boston University