Study of the Pathogenicity of a Eromonas Hydrophila for Man

Abstract

A pool of volunteers from the Houston Community were attracted to our Institution for efficient study in the Hospital. Three strains of A. hydrophila were selected for study in volunteers based on recovers from patients in well defined studies; laboratory studies of the presence of virulence propeties; Recovery from selective media; and antibiorgrams. The tests strains were fed to 5 groups of volunteers in doses ranging from 10,000 to 10 million viable cells. Transient excretion of the test strain rarely occured in any group and, despite the passage of several soft and rare watery stools by four volunteers, frank illness did not develop. We are currently looking at the development of humoral antibodies in the volunteers and are feeding the test strains in a dose of 100 million viable cells.

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Document Details

Document Type
Technical Report
Publication Date
Aug 15, 1983
Accession Number
ADA171380

Entities

People

  • Herbert L. Dupont

Organizations

  • University of Texas Health Science Center at Houston

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Biomedical Research
  • Blood
  • Cells
  • Chemical Analysis
  • Contracts
  • Cytotoxins
  • Diarrhea
  • Diseases And Disorders
  • Health Services
  • Hospitals
  • Infection
  • Intestines
  • Medical Personnel
  • Medical Screening

Readers

  • Immunology
  • Microbial Pathology
  • Technical Research and Report Writing.