Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage.

Abstract

Laser spectroscopy experiments have focused on cones in the red-eared swamp turtle, Pseudemys scripta elegans. Our choice of this system was based on the desire to correlate our molecular data with the extensive data being collected on this system by Dr. Zwick in his studies on laser hazards at LAIR. Thus, a detailed collaborative effort was initiated on this system during the past year. The experiments have already resulted in important information which opens new avenues to explore fundamental molecular mechanisms of retinal damage with laser irradiation. Results of these experiments will be summarized in the following sections: I. Elucidation of the role of oil droplets in the absorption of light by the turtle retina; II. A Selective Probe of Membrane Potentials in Turtle Cone Cells; III. Angstrom Resolution Light Microscopy of Photoreceptor Cells; IV. Identification and Selective Staining of Other Important Molecular Components of Photoreceptor Cells.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA171645

Entities

People

  • Aaron Lewis

Organizations

  • Cornell University

Tags

DTIC Thesaurus Topics

  • Absorption
  • Absorption Spectra
  • Cells
  • Chemistry
  • Frequency
  • Fungi
  • Laser Spectroscopy
  • Lasers
  • Membrane Potentials
  • Microscopy
  • Pigments
  • Raman Spectra
  • Raman Spectroscopy
  • Scattering
  • Spectra
  • Spectroscopy
  • Vibrational Spectra

Fields of Study

  • Physics

Readers

  • Oncology (Cancer Research).
  • Theoretical Analysis.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Directed Energy