Tendon Fibroplasia Induction by Exogenous Electrical Fields.

Abstract

A parametric study is being undertaken of the effects of extra low frequency (ELF) conductive electric fields on chicken tendon explant fibroplasia, collagen synthesis and oriented migration. Independent variables are: pulse repetition rate, pulse duration, peak current density (or electric field strength), explant orientation (with respect to E field) and donor (chicken) age. ELF pulsed electric fields with average current densities in the range of 0.18 to 5.7 micro A/sq cm induced statistically significant alternations in fibroblast proliferation with a windowed response of peak stimulation of proliferation in the range of 0.4 to micro A/sq cm, and suppression at higher current densities.

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Document Details

Document Type
Technical Report
Publication Date
Aug 10, 1986
Accession Number
ADA172279

Entities

People

  • Li-ming Liu
  • Robert Diegelmann
  • Stephen F. Cleary

Organizations

  • Virginia Commonwealth University School of Medicine

Tags

DTIC Thesaurus Topics

  • Availability
  • Biophysics
  • Cell Movement
  • Cells
  • Classification
  • Collagen
  • Contracts
  • Culture Media
  • Current Density
  • Electric Fields
  • Frequency
  • Orientation (Direction)
  • Physiology
  • Polarity
  • Repetition Rate
  • Security
  • Virginia

Readers

  • Cardiovascular Physiology
  • Electromagnetic Wave Scattering and Antenna Radiation Engineering
  • Pulsed Power and Plasma Physics.