Lassa Fever Immune Plasma.

Abstract

122 Units of plasma were obtained in Liberia from convalescents from Lassa fever. 98 units were forwarded to the USAMRIID for its use, of these, 59 were found to have Log Neutralization titers of 00.3 or higher, indicating a protective value against Lassa fever (LF) adequate for the use of USAMRIID. Surveys of patient sera in a number of hospitals indicated that as many as 15% of adults admitted for fever had LF. Surveys of hospital staffs throughout Liberia indicated that LF is endemic in all parts of the country. Surveys of village populations revealed prevalences of Lassa virus (LV) antibodies at a titer of 1:8 or more by the indirect fluorescent antibody technique. Prevalences were higher in roadside villages than in villages in the bush. LV was isolated 38 times from 31 patients in specimens forwarded to USAMRIID. At least one virus type was found differing from that previously discovered in nearby Sierra Leone.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1983
Accession Number
ADA172463

Entities

People

  • John D. Frame

Organizations

  • Columbia University

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Biomedical Research
  • Blood
  • Diseases And Disorders
  • Families (Human)
  • Filter Paper
  • Geographic Regions
  • Health
  • Health Services
  • Hospitals
  • Lassa Fever
  • Medical Personnel
  • New York
  • Plastic Explosives
  • Public Health
  • United States
  • Virus Diseases

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  • Archaeological Resource Survey
  • Virology (or Medical Virology).