Neurophysiological Bases of Event-Related Potentials.

Abstract

In order to more fully understand the physiological and psychological significance of event-related brain potentials, cortical and subcortical recordings were obtained from monkeys performing an operant conditioning task (cued reaction time). During the past year three cynomolgus monkeys were studied following the administration of MPTP, a drug that selectively destroys nigra-striatal dopaminergic neurons in the pars compacta of the substantia nigra. This manipulation indicated the critical role of the nigra-striatal dopamine for task performance enhancement would be to determine if increasing nigra-striatal dopaminergic activity would enhance performance and electrophysiological responsivity. Keywords: Subcortical Nuclei; Biocybernetics; Cognition; Reaction Time.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 08, 1986
Accession Number
ADA172995

Entities

People

  • Charles S. Rebert

Organizations

  • SRI International

Tags

Communities of Interest

  • Biomedical
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Biological Sciences
  • Brain
  • Cells
  • Central Nervous System
  • Cognition
  • Cognitive Workload
  • Human-Machine Systems
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Medical Personnel
  • Nervous System
  • Neurons
  • Neurophysiology
  • Neurosciences
  • Psychology
  • Psychophysiology
  • Reaction Time

Fields of Study

  • Biology
  • Psychology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.