Hemodynamics of Miniature Swine during +G sub z Stress with and without Anti-G Support

Abstract

Nine unanesthetized, chronically instrumented, female miniature swine (MS) (avg wt, 39.7 kg) were exposed to head-to-tail inertial load (G sub z) levels of +3,+5, and +7 G sub z for 60 s, with and without anti-G-suit inflation. Venous flow (VF) was measured by an electromagnetic flow sensor around the inferior thoracic vena cava at the diaphragm. Central venous pressure (CVP), abdominal venous pressure (AVP), eye-level blood pressure (ELBP) and esophageal pressure (EP ) were also measured before, during, and after G sub z. There was a progressive significant decreased from control of both ELBP (P 0. 001) and VF (P 0.05) during the three G sub z exposures, both with and without S-suit inflation. The MS does a spontaneous straining maneuver (cyclic Valsalva) during G sub z with G-suit support. Using EP as aa trigger, the data were grouped as strain or no strain (relaxation). A continuous AVP-to-CVR gradient existed during G-suit inflation, which increased dramatically during no strain with increasing G sub z, and was associated with an increase in VF. Thus, the majority of VF occurred during relaxation between strains, even though relaxation time was shortened as G sub z increased.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1986
Accession Number
ADA173304

Entities

People

  • John W. Burns
  • Michael J. Parnell
  • Russell R. Burton

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms
  • Sensors
  • Space

DTIC Thesaurus Topics

  • Air Force
  • Anesthesia
  • Blood
  • Blood Flow
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Data Science
  • Heart Rate
  • Hemorrhagic Shock
  • Medical Personnel
  • Pressure Gradients
  • Protective Equipment
  • Veins
  • Vena Cava

Readers

  • Cardiovascular Physiology
  • Mechanical Engineering/Mechanics of Materials.