Preliminary Assessment of the Relative Toxicity of AI3-36161 in Animals.
Abstract
Preliminary toxicity data are presented for Candidate cockroach repellent AI3-36161. These data are intended to provide guidance in selecting compounds for further entomological and toxicological evaluations. The rat oral approximate lethal dose was found to be 987 mg/kg. This compound caused moderate to severe skin and eye irritation in rabbits. It was not mutagenic in the Ames test and was not a sensitizer in guinea pigs. A number of cardiovascular alterations were noted in anesthetized rats injected with sublethal doses of AI3-36161. This compound was not an inhalation hazard at room temperature; however, if heated, its vapors may reach concentrations which could cause skin, eye and respiratory irritation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1986
- Accession Number
- ADA173373
Entities
People
- Glenn J. Leach
Organizations
- United States Army Medical Command